CD14 promoter polymorphism and atopic phenotypes in Czech young patients with IgE-mediated allergy

• Authors: BUČKOVÁ Dana; IZAKOVIČOVÁ HOLLÁ Lydie; SCHÜLLER Marcel; ZNOJIL Vladimír
• Year of publication: 2004
• Type: Article in Proceedings
• Conference: Abstract Book
• MU Faculty or unit: Faculty of Medicine
• Field: Immunology
• Keywords: CD14; gene; polymorphism; IgE; allergy
• Description: Atopy is a generally considered to be caused by interaction of genetic and environmental factors. The gene encoding CD14 is a positional candidate gene for atopy, as it is localized on chromosome 5q31.1, a region that has been linked to asthma and atopic responses. The present study was conducted to determine the association of -1145A/G polymorphism with atopic phenotypes in the Czech population.

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