Publication details

Comparison of risks of pulmonary embolism for ambulatory treatment of deep venous thrombosis and treatment of patients with deep venous thrombosis in St.Ann's Universitary Hospital Brno, Czech Republic

Authors

SOCHOR Ondřej HOFÍREK Ivo

Year of publication 2005
Type Article in Periodical
Magazine / Source Kardiológia
MU Faculty or unit

Faculty of Medicine

Citation
Field Cardiovascular diseases incl. cardiosurgery
Keywords deep venous thrombosis-pulmonary embolism-AlLMWH-warfarin
Description Aim: To compare risks of pulmonary embolism (PE) for ambulatory treatment of deep venous thrombosis (DVT) and treatment of patients with DVT in St.Anns Universitary Hospital Brno, Czech Republic. Methods: We compared two groups of patients with DVT : first group of them were treated from XI/1993 to XII/2003 by ambulatory treatement (LMWH in average for 11 days with transition to warfarin, INR 2-3, total 457 patients). The second group was formed by 100 patients hospitalised from I/2003 to XII/2004 in Cardioangiological Departement with DVT. Every patient had signs of DVT on duplex ultrasound and positive D-dimers. Results: In the first group, formed by 457 patients with mainly distal DVT (distal DVT-under knee had 318 of them), occured 15 pulmonary embolism, no one was submassive or massive. In the second group of 100 hospitalised patients, pulmonary embolism (verified by CT or scintigraphy) occured in 10 cases, no one was lethal. Every PE was detected following anamnesis and clinical symptoms at admission at hospital (allways with pain or dyspnea in medical records), except 2 asymptomatic patients included in study requiring pulmonary scintigraphy. One patient with DVT died on bronchopneumonia. Conclusion: Only 3% of our ambulatory patients with DVT suffered of pulmonary embolism. Among hospitalised patients with DVT, we observed 10 % of PE. The reason of this difference is probably evident selection of patients at the first contact, age of these patients, their co-morbidity and mobility.

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