Publication details
Azelaová kyselina v léčbě hyperpigmentací
| Title in English | Azelaic acid in treatment of abnormal hyperpigmentation skin |
|---|---|
| Authors | |
| Year of publication | 2007 |
| Type | Article in Periodical |
| Magazine / Source | Referátový výběr z dermatovenerologie |
| MU Faculty or unit | |
| Citation | |
| Field | Dermatovenerology |
| Keywords | azelaic acid; therapy; hyperpigmentary skin disorders |
| Description | Azelaic acid is a naturally occuring dicarboxylic acid. Azelaic acid reduces P. acnes proliferation, helps to normalize keratinization and may also have a direct antiinflammatory effects. Azelaic acid is a depigmentary agents - a competitive and reversible inhibitor of tyrosinase, the key enzyme of melanogenesis, thioredoxin reductase and mitochondrial enzymes. |