Publication details

Imunohistochemická analýza exprese cyklooxygenázy-2 v premaligních a maligních duktálních pankreatických lézích.

Title in English Immunohistochemical analysis of cyclooxygenase-2 expression in premalignant and malignant ductal pancreatic lesions.
Authors

HERMANOVÁ Markéta TRNA Jan NENUTIL Rudolf ŠEVČÍKOVÁ Arona DÍTĚ Petr

Year of publication 2008
Type Article in Periodical
Magazine / Source Česká a slovenská gastroenterologie a hepatologie
MU Faculty or unit

Faculty of Medicine

Citation
Field Other specializations of internal medicine
Keywords COX-2; chemoprevention; pancreatic carcinoma; PanIN
Description Immunohistochemical analysis of COX-2 expression showed significant expression of COX-2 in 52,9 % PanIN lesions and in 80 % pancreatic ductal adenocarcinomas. The results supported the concept of pancreatic cancer progression model and of the role of COX-2 in its oncogenesis.

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