Publication details

Analýza chirurgických operací na vena saphena magna v České republice a vliv podání Detralexu při jejím strippingu

Title in English Analysis of surgical procedures on the vena saphena magna in the Czech Republic and an effect of Detralex during its stripping
Authors

VEVERKOVÁ Lenka JEDLIČKA Václav WECHSLER Jan

Year of publication 2005
Type Article in Periodical
Magazine / Source Rozhledy v chirurgii
MU Faculty or unit

Faculty of Medicine

Citation
Field Surgery incl. transplantology
Keywords Varicose vein stripping flebotropic drugs symptoms of CVI pain quality of live
Description The aim of this clinical study was to compare the degree of postoperative pain, quality of life questionnaire and patient diary between two groups: patients treated with Detralex 14 days before and 14 days after the stripping of GSV and patients not treated with Detralex. Clinical study included 181 patients from 15 medical centers in the Czech republic. Patients were randomly assigned in two groups: patients treated with Detralex (92) and patients not treated with Detralex (89). The results indicate that Detralex reduced the intensity of postoperative pain, which resulted in decreased consumption of analgesics. Hematoma was smaller in patients already using Detralex 14 days prior to the scheduled stripping procedure. These patients also showed significant improvement of CVI. High quality venoactive drugs administered 14 days prior to the surgery improve postoperative course in patients indicated for surgical treatment of varices.

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