Publication details

Sledování bezpečnosti a účinnosti přípravku amisulpřidu (Solian) v podmínkách běžné klinické praxe

Title in English Monitoring safety and efficiency of the preparation amisulpride (Solian) in common clinical practice
Authors

ČEŠKOVÁ Eva SUCHOPÁR Josef

Year of publication 2009
Type Article in Periodical
Magazine / Source Česká a slovenská psychiatrie
MU Faculty or unit

Faculty of Medicine

Citation
Field Psychiatry, sexuology
Keywords amisulpride; adverse events; positive and negative symptoms in schizophrenia
Description The tolerability and safety of amisulpride has been followed for 3 months in 2 135 out-patients with schizophrenia. Totally 2 963 of side-effects in 1 243 treated were observed. 2 437 side effects were evaluted as mildly severe, 499 as moderately severe and 27 as severe. According to expectation, the most frequently obsarved side-effects were fatigue and drowsiness, further infomnia and anxiety of all side-effect). On the other side few prolactin- dependent side effects have been observed. Both positive and negative symptoms were improved during the 3-months therapy. With a mean daily dose of 476,6 +- 176,49 ng a very giid abd giid effect ib begatuve symptoms was seen in 88,43 % if treatedm ib oisutuve synotins ub 88,24 % of treated.
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