Publication details
Imunohistochemickká analýza exprese cyklooxygenázy-2 v premaligních a maligních duktálních panktreatických lézích
| Title in English | Immunohistochemical analysis of cyklooxygenase 2 expression in premalignant and malignant ductal pancreatic lesions |
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| Authors | |
| Year of publication | 2008 |
| Type | Article in Periodical |
| Magazine / Source | Česká a slovenská gastroenterologie a hepatologie |
| MU Faculty or unit | |
| Citation | |
| Field | Other specializations of internal medicine |
| Keywords | COX2-chemoprevention-pancreatic carcinoma-PanIN |
| Description | Cyclooxygenase - 2 (COX-2) is an enzyme, which plays a key role in processes of inflammation and carcinogenesis. It represents a molecule intimately linked to the oncogenesis of panreatic ductal adenocarcinoma, which is a multistep praces characterized by the progression from normal dustal epithelium through the spectrum of non-invasive pancreatic ductal intraepithelial neoplasias (PanINs) to structures of invasive adenocarcinoma. |