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Prognostický a prediktivní význam exprese EGFR, HER2-neu a genetických alterací v EGFR signální cestě u spinocelulárních karcinomů hlavy a krku
Title in English | Prognostic and predictive value of genetic alterations in EGFR signal pathway in spinocellular head and neck cancers |
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Authors | |
Year of publication | 2009 |
Type | Article in Periodical |
Magazine / Source | Otorinolaryngologie a foniatrie |
MU Faculty or unit | |
Citation | |
Field | ORL, ophthalmology, stomatology |
Keywords | EGFR gene amplification k-ras mutation tyrosine kinase mutation chemoradiotherapy predictive marker |
Description | This study is about EGFR expression and genetic alterations in EGFR signal pathway in correlation with therapeutical response in head and neck cancers. Mentioned meaning of k-ras mutation, EGFRvIII, tyrosinkinase domain. |