Publication details

Prognostický a prediktivní význam exprese EGFR, HER2-neu a genetických alterací v EGFR signální cestě u spinocelulárních karcinomů hlavy a krku

Title in English Prognostic and predictive value of genetic alterations in EGFR signal pathway in spinocellular head and neck cancers
Authors

NEUWIRTHOVÁ Jana SMILEK Pavel BERKOVCOVÁ Jitka ROTTENBERG Jan KOSTŘICA Rom HAJDÚCH Marian TROJANEC Radek

Year of publication 2009
Type Article in Periodical
Magazine / Source Otorinolaryngologie a foniatrie
MU Faculty or unit

Faculty of Medicine

Citation
Field ORL, ophthalmology, stomatology
Keywords EGFR gene amplification k-ras mutation tyrosine kinase mutation chemoradiotherapy predictive marker
Description This study is about EGFR expression and genetic alterations in EGFR signal pathway in correlation with therapeutical response in head and neck cancers. Mentioned meaning of k-ras mutation, EGFRvIII, tyrosinkinase domain.

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