Publication details

Successful treatment of steroid-refractory hepatitic variant of liver graft-vs host disease with pulse cyclophosphamide

Authors

MAYER Jiří KREJČÍ Marta POSPÍŠIL Zdeněk DOUBEK Michael JANÍKOVÁ Andrea ŽÁČKOVÁ Daniela RÁČIL Zdeněk ŠMARDOVÁ Lenka NAVRÁTIL Milan KAMELANDER Jan

Year of publication 2009
Type Article in Periodical
Magazine / Source Experimental Hematology
MU Faculty or unit

Faculty of Medicine

Citation
Field Oncology and hematology
Keywords steroid refractory hepatitic variant; pulse cyclophosphamide
Description Corticosteroid-resistant graft-vshost disease (GVHD) is difficult to manage and is associated with high morbidity and mortality. No standard treatment exists. We have previously seen good result with pulse cyclophosphamide (cy) in the treatment of liver GVHD in contrast to gastrointestinal GVHD, and here we report results of pulse Cy protocol in the treatment of steroid-refractory hepatitic variant of liver GVHD, with no association to the gut.
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