Publication details

Endocannabinoid Brain System Involvement in dopamine mechanisms of behavioural sensitization to psychostimulants

Authors

VRŠKOVÁ Dagmar

Year of publication 2009
Type Article in Periodical
Magazine / Source Acta veterinaria Brno
MU Faculty or unit

Faculty of Medicine

Citation
Web http://vfu-www.vfu.cz/acta-vet/archives/volume78/issue3/200978030491.html
Field Pharmacology and pharmaceutical chemistry
Keywords Behavioural sensitization;endocannabinoid system;dopamine;methamphetamine;review
Description The paper deals with the involvement of endocannabionid brain system in dopamine mechanisms of behavioural sensitization to psychostimulants. The development and manifestation of behavioural sensitization to methamphetamine are described. Results obtained in our previous studies, showing an interaction between the endocannabinoid system and methamphetamine brain mechanisms, in the rat intravenous drug self-administration model and with qPCR CB1 mRNA expression, are discussed.
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