Publication details

Large Randomised Clinical Trials and Regular Practice in a Tertiary Hepatology Centre

Authors

URBÁNEK Petr MAREČEK Zdeněk BRODANOVÁ Marie BRŮHA Radan PETRTÝL Jaromír DUŠEK Ladislav

Year of publication 2008
Type Article in Periodical
Magazine / Source Česká a slovenská gastroenterologie a hepatologie
MU Faculty or unit

Faculty of Medicine

Citation
Field Epidemiology, infectious diseases and clinical immunology
Keywords hepatitis C;pegylated interferon;ribavirin
Description Treatment efficacy of chronic HCV infection published by Fried et al. seems to be quite comparable to the efficacy achieved in our group of patients treated by the same type of therapy. These results were obtained despite of several differences in groups being compared - different PCR techniques, differences in patient races and slightly different protocol of routine treatment. Our results support the importance of transmission of clinical trial results based on principles of Evidence Based Medicine for routine practice.

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