Vang-like protein 2 and Rac 1 interact to regulate adherens junctions

• Authors: LINDQVIST Maria; HORN Zachi; BRYJA Vítězslav; SCHULTE Gunnar; PAPACHRISTOU Panagiotis; AJIMA Rieko; DYBERG Cecilia; ARENAS Ernest; YAMAGUCHI Terry P; LAGERCRANTZ Hugo; RINGSTEDT Thomas
• Year of publication: 2010
• Type: Article in Periodical
• Magazine / Source: JOURNAL OF CELL SCIENCE
• MU Faculty or unit: Faculty of Science
• Field: Genetics and molecular biology
• Keywords: Cell adhesion; Neurulation; PCP; Wnt
• Description: The Wnt Planar Cell Polarity (PCP) pathway signals through small Rho-like GTPases to regulate the cytoskeleton. Here we investigate the function of the mammalian PCP protein Vangl2. We propose that Vangl2 affects cell adhesion and the cytoskeleton by recruiting Rac1 .

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