Publication details
Histiocytóza z Langerhansových buněk - kožní aspekty onemocnění
| Title in English | Langerhans cell histiocytosis - cutaneous aspects of the disease |
|---|---|
| Authors | |
| Year of publication | 2010 |
| Type | Article in Periodical |
| Magazine / Source | Vnitřní lékařství |
| MU Faculty or unit | |
| Citation | |
| Field | Dermatovenerology |
| Keywords | Langerhans cell histiocytosis; cutaneous lesions; treatment |
| Description | There is discussed nature of Langerhans cell histiocytosis -reactive versus neoplastic. It represents wide clinical spectrum with localised or disseminated types of the disease. Skin lesions are very common and they could be the first symptoms. Usually involved is the scalp and trunk area. The involvement of nails and mucous membranes is possible. From treatment modalities, PUVA (photochemotherapy) is very important and it is best mode is systemic admission of psoralen with subsequent irradiation by defined part of UVA range. It can be considered as the first choice treatment for skin lesions. |