Publication details

Prediktivní model karcinomů hlavy a krku – podklad pro rozhodnutí o léčbě?

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Title in English Molecular markers of head and neck cancer – a basis for treatment decision?
Authors

SMILEK Pavel

Year of publication 2010
Type Article in Proceedings
Conference 73. kongres České společnosti otorinolaryngologie a chrirugie hlavy a krku
MU Faculty or unit

Faculty of Medicine

Citation
Field ORL, ophthalmology, stomatology
Keywords Head and neck cancer; mitotic/apoptotic ratio; S phase fraction; treatment
Description The analysis was carried out with a set of 196 patients suffering from spinocellular cancer of the oral cavity, oropharynx, hypopharynx and larynx. Flow cytometric analysis of DNA, mitotic/apoptotic index, immunohistochemical determination of Ki-67, EGFR, c-erb B2, MMP 9, p53, bcl-2, and CD 34 was made in realation to choice of the way of treatment.
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