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Prediktivní model karcinomů hlavy a krku – podklad pro rozhodnutí o léčbě?
Title in English | Molecular markers of head and neck cancer – a basis for treatment decision? |
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Authors | |
Year of publication | 2010 |
Type | Article in Proceedings |
Conference | 73. kongres České společnosti otorinolaryngologie a chrirugie hlavy a krku |
MU Faculty or unit | |
Citation | |
Field | ORL, ophthalmology, stomatology |
Keywords | Head and neck cancer; mitotic/apoptotic ratio; S phase fraction; treatment |
Description | The analysis was carried out with a set of 196 patients suffering from spinocellular cancer of the oral cavity, oropharynx, hypopharynx and larynx. Flow cytometric analysis of DNA, mitotic/apoptotic index, immunohistochemical determination of Ki-67, EGFR, c-erb B2, MMP 9, p53, bcl-2, and CD 34 was made in realation to choice of the way of treatment. |
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