Publication details

Radioterapií indukované meningeomy

Title in English Radiation-induced meningiomas
Authors

JANČÁLEK Radim NOVÁK Zdeněk CHRASTINA Jan

Year of publication 2010
Type Article in Proceedings
Conference Edukační sborník
MU Faculty or unit

Faculty of Medicine

Citation
Keywords radiation-induced meningiomas, features, therapy
Description Recent radiotherapy is a standard procedure for treatment of both high-grade tumors of CNS and non-tumorous lesions. Despite its therapeutic potential, radiotherapy can act as a trigger for cancerogenesis. Meningiomas are the most frequent intracranial tumors induced by radiotherapy due to high radiosensitivity of meningeal tissue. Radiation-induced meningiomas differ from spontaneous meningiomas by its higher incidence in the younger age group. They are also more frequently multiple with histological abnormities and higher incidence of recurrence. First-choice therapy for radiation-induced meningiomas is a surgical treatment. Stereoradiosurgery appears to be choice for treatment of the progressive meningiomas in locations unsuitable for the surgical treatment. Three cases of radiation-induced meningiomas were found by retrospective study of patients treated at the Department of Neurosurgery, St. Anne’s University Hospital, Brno. In conclusion, radiation-induced meningiomas form a specific group of meningiomas. It is necessary to take account of their specific features during care for oncology patients.

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