Publication details

Healing of Large Segmental Bone Defect after Implantation of Autogenous Cancellous Bone Graft in Comparison to Hydroxyapatite and 0.5% Collagen Scaffold Combined with Mesenchymal Stem Cells

Authors

NEČAS Alois PROKS Pavel URBANOVÁ Lucie SRNEC Robert STEHLÍK Ladislav CRHA Michal RAUŠER Petr PLÁNKA Ladislav JANOVEC Jan DVOŘÁK Milan AMLER Evžen VOJTOVÁ Lucy JANČÁŘ Josef

Year of publication 2010
Type Article in Periodical
Magazine / Source Acta Veterinaria
MU Faculty or unit

Faculty of Medicine

Citation
Field Traumatology and orthopaedic surgery
Keywords Fracture fixation; bone healing; comminuted fracture; callus; ostectomy; buttress plate
Description No significant difference was found in the size of callus between animals of group S and animals of group S + MSCs. Unlike a scaffold in the shape of the original bone column, a freely placed autogenous cancellous bone graft may allow the newly formed tissue to spread more to the periphery of the ostectomy defect. Implanted cylindrical scaffolds (with and without MSCs) support callus formation directly in the center of original bone column in segmental femoral ostectomy, and can be successfully used in the treatment of large bone defects.
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