Healing of Large Segmental Bone Defect after Implantation of Autogenous Cancellous Bone Graft in Comparison to Hydroxyapatite and 0.5% Collagen Scaffold Combined with Mesenchymal Stem Cells

• Autoři: NEČAS Alois; PROKS Pavel; URBANOVÁ Lucie; SRNEC Robert; STEHLÍK Ladislav; CRHA Michal; RAUŠER Petr; PLÁNKA Ladislav; JANOVEC Jan; DVOŘÁK Milan; AMLER Evžen; VOJTOVÁ Lucy; JANČÁŘ Josef
• Rok publikování: 2010
• Druh: Článek v odborném periodiku
• Časopis / Zdroj: Acta Veterinaria
• Fakulta / Pracoviště MU: Lékařská fakulta
• Obor: Traumatologie a ortopedie
• Klíčová slova: Fracture fixation; bone healing; comminuted fracture; callus; ostectomy; buttress plate
• Popis: No significant difference was found in the size of callus between animals of group S and animals of group S + MSCs. Unlike a scaffold in the shape of the original bone column, a freely placed autogenous cancellous bone graft may allow the newly formed tissue to spread more to the periphery of the ostectomy defect. Implanted cylindrical scaffolds (with and without MSCs) support callus formation directly in the center of original bone column in segmental femoral ostectomy, and can be successfully used in the treatment of large bone defects.

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