Publication details
Léčba akutní exacerbace chronické obstrukční plicní nemoci za hospitalizace a na lůžku intenzivní péče
| Title in English | Treatment of acute exacerbation of the obstructive pulmonary disease with hospitalization at an Intensive Care Unit. |
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| Authors | |
| Year of publication | 2011 |
| Type | Article in Periodical |
| Magazine / Source | Vnitřní lékařství |
| MU Faculty or unit | |
| Citation | |
| Field | Other medical specializations |
| Keywords | acute exacerbation; bronchodilatation treatment; intensive care |
| Description | Bronchodilatation is preferably achieved with beta-2-agonists (SABA), salbutamol. Therapy is intensified with anticholinergics (ipratropium bromide monohydrate). A combined preparation may also be used (ipratropium bromide monohydrate and fenoterole hydrobromide). Methylxantines (theophylline) are the second line option. Corticosteroids are administered orally (prednisolone) or intravenously (methylprednisolone or hydrocortisone). Patients who have problems expectorating are administered mucolytics (ambroxol hydrochloride or bromhexine hydrochloride). Some patients are treated with antibiotics. Oxygenotherapy is indicated in patients with hypoxemia. Insufficient treatment effect and progression of respiratory insufficiency warrants application of mechanical or non-invasive ventilation. |