Publication details

Cetuximab v kombinaci s radioterapií jako metoda volby v první linii léčby lokoregionálně pokročilých karcinomů hlavy a krku - případy z praxe

Title in English Cetuximab in combination with radiotherapy as method of choice in first-line treatment for locoregionally advanced head and neck cancers – cases from practice
Authors

NEUWIRTHOVÁ Jana SMILEK Pavel KOSTŘICA Rom

Year of publication 2011
Type Article in Periodical
Magazine / Source Klinická onkologie
MU Faculty or unit

Faculty of Medicine

Citation
Field Oncology and hematology
Keywords cetuximab; HNSCC; locoregionally advanced head and neck cancers; double tumour; organ-preserving protocol; predictive markers; K-ras
Description Cetuximab whose lower toxicity is a clear benefit compared to chemotherapy is the only agent registered for the targeted therapy of squamous cell head and neck cancers. Given the high complete remission rate in locoregionally advanced disease in our cohort, our experience with this treatment is very good. In addition to clinical observation, research into predictive markers is under development.

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