Publication details
Vitamin D a frailty
| Title in English | Vitamin D and frailty |
|---|---|
| Authors | |
| Year of publication | 2011 |
| Type | Article in Periodical |
| Magazine / Source | Interní medicina pro praxi |
| MU Faculty or unit | |
| Citation | |
| Field | Other specializations of internal medicine |
| Keywords | frailty; vitamin D; bone; muscle; sarcopenia; cognitive functions; depression; cancer; autoimunity; diabetes mellitus |
| Description | Frailty syndrome comprises not only emerging fractures caused by instability and falls, but complex of pathologies as frequent organ decompensations, infective complications, psychical problems and rapid cognitive decline accelerating the appearance of disability and dependency of seniors. Vitamin D as one of liposolubile vitamins was related to children age and skeleton at the clinical practice until now. There is lot of new information considering rather more complicated connection of vitamin D into many functions of human body during last years. On the other hand we are able to measure the serum level of vitamin D, so we recognized the possibility of long term significantly low levels of vitamin D in tenths percent of population. This review shows actual information about relationsship between vitamin D and organ systems and their disturbances. Long term low level of vitamin D potentiates cognitive deterioration in elderly, influences the mood up to depression appearance. The influence of vitamin D on imunity system and cancerogenesis appears to be of high importance too. From the seniors independence point of view the relationship between vitamin D and sarcopenia is very important especially in connection with osteoporosis prevention - the way how to reduce the danger of falls and osteoporotic fractures. Autoimmune diseases and diabetes mellitus are mentioned at the end of the review. |