Publication details

Intramolecular and intermolecular guanine quadruplexes of DNA in aqueous salt and ethanol solutions

Authors

VORLÍČKOVÁ Michaela BEDNÁŘOVÁ Klára KEJNOVSKÁ Iva KYPR Jaroslav

Year of publication 2007
Type Article in Periodical
Magazine / Source Biopolymers
MU Faculty or unit

Faculty of Science

Citation
Web http://onlinelibrary.wiley.com/doi/10.1002/bip.20672/pdf
Doi http://dx.doi.org/10.1002/bip.20672
Field Biophysics
Attached files
Description DNA guanine quadruplexes are all based on stacks of guanine tetrads, but they can be of many types differing by mutual strand orientation, topology, position and structure of loops, and the number of DNA molecules constituting their structure. In this article we have studied a series of nine DNA fragments (G3Xn)3G3, where X=A, C or T, and n=1, 2 or 3, to find how the particular bases and their numbers enable folding of the molecule into quadruplex and what type of quadruplex is formed.

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