Informace o projektu
Czech Infrastructure for Integrative Structural Biology
(CIISB)
- Kód projektu
- LM2015043
- Období řešení
- 1/2016 - 12/2019
- Investor / Programový rámec / typ projektu
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Ministerstvo školství, mládeže a tělovýchovy ČR
- Velké infrastruktury pro výzkum, vývoj a inovace
- Fakulta / Pracoviště MU
-
Středoevropský technologický institut
- prof. RNDr. Vladimír Sklenář, DrSc.
The Czech Infrastructure for Integrative Structural Biology (CIISB) is a distributed infrastructure of the core facilities and central laboratories of CEITEC (Central European Institute of Technology, Brno) and BIOCEV (Biotechnology and Biomedicine Centre, Vestec, Prague-West) providing expertise and access to technologies used for integrative approaches to structural analysis of biologically important cellular components and macromolecules - proteins, nucleic acids, and their complexes. CIISB, equipped with the cutting-edge technologies (total investments will exceed 750 mil. CZK by the end of 2015), will offer access to the equipment and expertise in the following fields: high-field NMR spectroscopy; high throughput crystallization of biological macromolecules; X-ray diffraction techniques; Bio-SAXS measurements; AFM imaging; characterization of proteins, nucleic acids and complexes by biophysical methods including microcalorimetry, dynamic light scattering, and surface plasmon resonance; high-end cryo-electron microscopy and tomography allowing studies of cellular structures, organelles, and biomacromolecular complexes by 3D imaging; protein expression in eukaryotic cells; high-end mass spectrometry characterization of biomacromolecules; determination of protein post-translational modifications; MS-based peptide mapping/sequencing; high throughput sequencing and proteomic services. CIISB infrastructure aims to provide a high quality open access services in provision of methods and techniques on a level of national and trans-national importance. CIISB as National Affiliated Center is a part of the ESFRI projects INSTRUCT.
Publikace
Počet publikací: 251
2018
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Generation of a Close-to-Native In Vitro System to Study Lung Cells-Extracellular Matrix Crosstalk
TISSUE ENGINEERING PART C-METHODS, rok: 2018, ročník: 24, vydání: 1, DOI
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Graphene Oxide from Improved Hummers' Method: Is This Material Suitable for Reproducible Electrochemical (Bio)Sensing?
ECS Journal of Solid State Science and Technology, rok: 2018, ročník: 7, vydání: 10, DOI
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Hexanuclear iron(III) alpha-aminophosphonate: synthesis, structure, and magnetic properties of a molecular wheel
New Journal of Chemistry, rok: 2018, ročník: 42, vydání: 3, DOI
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Human RAD51 rapidly forms intrinsically dynamic nucleoprotein filaments modulated by nucleotide binding state
Nucleic Acids Research, rok: 2018, ročník: 46, vydání: 8, DOI
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HYBRID MESOPOROUS NON-SILICA CATALYST SUPPORTS BY NON-HYDROLYTIC SOL-GEL METHODS
Rok: 2018, druh: Další prezentace na konferencích
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HYBRID MESOPOROUS NON-SILICA CATALYST SUPPORTS BY NON-HYDROLYTIC SOL-GEL METHODS
Rok: 2018, druh: Konferenční abstrakty
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Hyperfine Effects in Ligand NMR: Paramagnetic Ru(III) Complexes with 3-Substituted Pyridines
Inorganic Chemistry, rok: 2018, ročník: 57, vydání: 2, DOI
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Changes of electrocatalytic response of bovine serum albumin after its methylation and acetylation
Journal of Electroanalytical Chemistry, rok: 2018, ročník: 821, vydání: JUL, DOI
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Chemical Identification in the Nanoscale - With AFM-IR and SSNOM
Rok: 2018, druh: Uspořádání workshopu
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Chiral Bambusurils for Enantioselective Recognition of Carboxylate Anion Guests
Chemistry - A European Journal, rok: 2018, ročník: 24, vydání: 58, DOI