ARResT/Interrogate: an interactive immunoprofiler for IG/TR NGS data

• Autoři: BYSTRÝ Vojtěch; REIGL Tomáš; KREJČÍ Adam; DEMKO Martin; HANÁKOVÁ Barbora; GRIONI Andrea; KNECHT Henrik; SCHLITT Max; DREGER Peter; SELLNER Leopold; HERRMANN Dietrich; PINGEON Marine; BOUDJOGHRA Myriam; RIJNTJES Jos; POTT Christiane; LANGERAK Anton W.; GROENEN Patricia J. T. A.; DAVI Frederic; BRUGGEMANN Monika; DARZENTAS Nikos
• Rok publikování: 2017
• Druh: Článek v odborném periodiku
• Časopis / Zdroj: Bioinformatics
• Fakulta / Pracoviště MU: Středoevropský technologický institut
• www: https://academic.oup.com/bioinformatics/article-abstract/33/3/435/2580414/ARResT-Interrogate-an-interactive-immunoprofiler?redirectedFrom=fulltext
• Doi: http://dx.doi.org/10.1093/bioinformatics/btw634
• Obor: Biochemie
• Klíčová slova: REPERTOIRE
• Popis: Motivation: The study of immunoglobulins and T cell receptors using next-generation sequencing has finally allowed exploring immune repertoires and responses in their immense variability and complexity. Unsurprisingly, their analysis and interpretation is a highly convoluted task. Results: We thus implemented ARResT/Interrogate, a web-based, interactive application. It can organize and filter large amounts of immunogenetic data by numerous criteria, calculate several relevant statistics, and present results in the form of multiple interconnected visualizations.

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• CERIT Scientific Cloud
• Velká infrastruktura CESNET
• Encyklopedie CLL podskupin: unikátní znalostní databáze vybavená bioinformatickými nástroji použitelná v personalizované biomedicíně a klinické praxi
• CEITEC 2020