Informace o publikaci
Machine Learning Survival Models for Relapse Prediction in a Early Stage Lung Cancer Patient
| Autoři | |
|---|---|
| Rok publikování | 2023 |
| Druh | Článek ve sborníku |
| Konference | 2023 INTERNATIONAL JOINT CONFERENCE ON NEURAL NETWORKS, IJCNN |
| Fakulta / Pracoviště MU | |
| Citace | |
| Doi | http://dx.doi.org/10.1109/IJCNN54540.2023.10191078 |
| Klíčová slova | survival; time; event; prediction; cancer; explanation |
| Popis | Lung cancer is one of the leading health complications causing high mortality worldwide. The relapsing behavior of medically treated early-stage lung cancer makes this disease even more complicated. Thus predicting such relapse using a data-centric approach provides a complementary perspective for clinicians to understand the disease. In this preliminary work, we explored off-the-shelf survival models to predict the relapse of early-stage lung cancer patients. We analyzed the survival models on a cohort of 1348 early-stage non-small cell lung cancer (NSCLC) patients in different timestamps. Using the prediction explanation model SHAP (SHapley Additive exPlanations), we further explained the best-performing survival model's predictions. Our explainable predictive model is a potential tool for oncologists that address an unmet clinical need for post-treatment patient stratification based on the relapse hazard. |