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Cell Nuclei Segmentation Using Star-Shaped Simplex Meshes

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MATULA Pavel SVOBODA David

Rok publikování 2002
Druh Článek ve sborníku
Konference Biophysics of the Genome and Its Interactions
Fakulta / Pracoviště MU

Fakulta informatiky

Citace
Obor Využití počítačů, robotika a její aplikace
Klíčová slova Cell nuclei segmentation; simplex meshes; deformable models
Popis Fast, reliable and precise cell nucleus boundary reconstruction algorithm is needed for automatic measuring of topographical parameters of the large number of cells or cell nuclei. A reconstruction method based on deformation of star-shaped simplex meshes is presented. The method was used for shape reconstruction of cell nuclei of HL-60 cells stained by DAPI (the whole volume of nuclei was visible in the input 3D images) and cell nuclei of HT-29 cells (nuclear envelope, i.e. surface of nucleus boundary, was visualized using Lamin B)
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