Informace o publikaci
Caffeic acid affects an induced differentiation process into granulocyte stage in HL-60 myeloid leukaemia cell line
| Autoři | |
|---|---|
| Rok publikování | 2002 |
| Druh | Článek ve sborníku |
| Konference | Cells IV |
| Fakulta / Pracoviště MU | |
| Citace | |
| Obor | Morfologické obory a cytologie |
| Klíčová slova | induced differentiation; apoptosis; MTT-assay; HL-60 cell line; caffeic acid; retinoic acid; dimethyl sulfoxide |
| Popis | The aim of presented study was to investigate possible effect of caffeic acid (CA) in combination with known differentiating agents, all-trans retinoic acid (ATRA) or dimethylsulfoxide (DMSO) respectively, on the HL-60 human myeloid leukemia cell line. Treatment of the HL-60 cells by CA in combination with known differentiation inductors ATRA and DMSO leads to the reduction of cell viability and increased frequency of apoptosis. |
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