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Effect of methamphetamine and fluoxetine combination on behavioural activity in wistar albino rats
Název česky | Vliv kombinace fluoxetinu a metamfetaminu na behaviorání aktivitu u potkana kmene Wistar |
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Autoři | |
Rok publikování | 2002 |
Druh | Článek v odborném periodiku |
Časopis / Zdroj | Bratislavské lekárské listy |
Fakulta / Pracoviště MU | |
Citace | |
www | http://www.bmj.cz |
Obor | Farmakologie a lékárnická chemie |
Klíčová slova | fluoxetine; methamphetamine; behaviour; rat |
Popis | Locomotor / exploratory behavioural changes were followed in Wistar rats pretreated with methamphetamine, fluoxetine or their combination. An "open field" (Acti-track, Panlab, Spain) was used as the tracking arena. Methamphetamine significantly increased all measured behavioural parameters while fluoxetine showed inhibitory effects. Pretreatment with combination of these drugs resulted in a more profound inhibition of locomotor activity than in fluoxetine given alone. |
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