Informace o publikaci
Human nucleosomes: special role of CG dinucleotides and Alu-nucleosomes
| Autoři | |
|---|---|
| Rok publikování | 2011 |
| Druh | Článek v odborném periodiku |
| Časopis / Zdroj | BMC Genomics |
| Fakulta / Pracoviště MU | |
| Citace | |
| www | http://www.biomedcentral.com/1471-2164/12/273 |
| Doi | http://dx.doi.org/10.1186/1471-2164-12-273 |
| Obor | Genetika a molekulární biologie |
| Klíčová slova | NUCLEOTIDE-SEQUENCE; DNA METHYLATION; CHROMATIN DNA; PATTERN; ELEGANS; CORE; RESOLUTION; POSITION; ELEMENTS; GENOME |
| Popis | The periodical occurrence of dinucleotides with a period of 10.4 bases now is undeniably a hallmark of nucleosome positioning. Considering the exceptional role CG dinucleotides play in the nucleosome positioning, we hypothesize that Alu-nucleosomes, especially, those that form tightly positioned runs, could serve as "anchors" in organizing the chromatin in human cells. |
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