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"Anticipated" nucleosome positioning pattern in prokaryotes
Autoři | |
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Rok publikování | 2011 |
Druh | Článek v odborném periodiku |
Časopis / Zdroj | Gene |
Fakulta / Pracoviště MU | |
Citace | |
Doi | http://dx.doi.org/10.1016/j.gene.2011.08.002 |
Obor | Genetika a molekulární biologie |
Klíčová slova | Amphipathic alpha helices; Evolution of nucleosome positioning pattern; Hidden sequence patterns; Sequence periodicity; Shannon N-gram extension |
Popis | Linguistic (word count) analysis of prokaryotic genome sequences, by Shannon N-gram extension, reveals that the dominant hidden motifs in A+T rich genomes are T(A)(T)A and G(A)(T)C with uncertain number of repeating A and T. In this case the above patterns in prokaryotes may be considered as "anticipated" nucleosome positioning patterns which, quite likely, existed in prokaryotic genomes before the evolutionary separation between eukaryotes and prokaryotes. |
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