doc. Mgr. Kamil Paruch, Ph.D.

2017

• Diastereoselective Flexible Synthesis of Carbocyclic C Nucleosides

  MAIER Lukáš KHIRSARIYA PrashantKumar HYLSE Ondřej ADLA Santosh Kumar ČERNOVÁ Lenka POLJAK Michal KRAJČOVIČOVÁ Soňa WEIS Erik DRÁPELA Stanislav SOUČEK Karel PARUCH Kamil

  Article in Periodical

  The Journal of Organic Chemistry, year: 2017, volume: 82, edition: 7, DOI

• Direct nanopatterning of biomolecules by electron beam lithography for studying of cellular interaction

  POSPÍŠIL Jakub OBOŇA Josef Vincenc HRABOVSKÝ Miloš MLČOUŠKOVÁ Jarmila KREJČÍ Kateřina BIDMANOVÁ Šárka PARUCH Kamil DAMBORSKÝ Jiří HAMPL Aleš JAROŠ Josef

  Conference abstract

  Year: 2017, type: Conference abstract

• Explicit treatment of active-site waters enhances quantum mechanical/implicit solvent scoring: Inhibition of CDK2 by new pyrazolo[1,5-a]pyrimidines

  HYLSOVÁ Michaela CARBAIN Benoit, Jean-Pierre FANFRLIK Jindřich MUSILOVÁ Lenka HALDAR Susanta KOPRULUOGLU Cemal AJANI Haresh BRAHMKSHATRIYA Pathik JORDA Radek KRYŠTOF Vladimír HOBZA Pavel ECHALIER Aude PARUCH Kamil LEPŠÍK Martin

  Article in Periodical

  European Journal of Medicinal Chemistry, year: 2017, volume: 126, edition: January, DOI

• Flow cytometric analysis of nucleoside transporters activity

  DRÁPELA Stanislav FEDR Radek KHIRSARIYA PrashantKumar PARUCH Kamil SOUČEK Karel

  Conference abstract

  Year: 2017, type: Conference abstract

• Chk1 Inhibitor SCH900776 Effectively Potentiates the Cytotoxic Effects of Platinum-Based Chemotherapeutic Drugs in Human Colon Cancer Cells

  HERŮDKOVÁ Jarmila PARUCH Kamil KHIRSARIYA PrashantKumar SOUČEK Karel KRKOŠKA Martin VONDÁLOVÁ BLANÁŘOVÁ Olga SOVA Petr KOZUBÍK Alois HYRŠLOVÁ VACULOVÁ Alena

  Article in Periodical

  Neoplasia, year: 2017, volume: 19, edition: 10, DOI

• INHIBITION OF CHK1 STIMULATES THE COOPERATIVE CYTOTOXIC ACTION OF PLATINUM-BASED DRUGS AND TRAIL IN HUMAN PROSTATE CANCER CELLS

  KRKOŠKA Martin HERŮDKOVÁ Jarmila BLANÁŘOVÁ O Vondálová PARUCH Kamil SOVA P HYRŠLOVÁ VACULOVÁ Alena

  Conference abstract

  Year: 2017, type: Conference abstract

• Kompletní analýza vlastností nových inhibitorů kasein kinázy 1 pro léčbu chronické lymfocytární leukémie

  BRYJA Vítězslav JANOVSKÁ Pavlína PARUCH Kamil NĚMEC Václav GREGOROVÁ Michaela

  Year: 2017, type:

• Pyrazolotriazines as inhibitors of nucleases

  PARUCH Kamil CARBAIN Benoit, Jean-Pierre HAVEL Štěpán DAMBORSKÝ Jiří BREZOVSKÝ Jan DANIEL Lukáš SISÁKOVÁ Alexandra NIKULENKOV Fedor KREJČÍ Lumír

  Patent

  Publisher: European Patent Office, state: Germany, patent's number: EP2957562, year: 2017

• Structural Basis of the Interaction of Cyclin-Dependent Kinase 2 with Roscovitine and Its Analogues Having Bioisosteric Central Heterocycles

  NEKARDOVÁ Michaela VYMĚTALOVÁ Ladislava KHIRSARIYA Prashant Kumar KOVÁČOVÁ Silvia HYLSOVÁ Michaela JORDA Radek KRYŠTOF Vladimír FANFRLÍK Jindřich HOBZA Pavel PARUCH Kamil

  Article in Periodical

  ChemPhysChem, year: 2017, volume: 18, edition: 7, DOI

• Synthesis and Profiling of a Novel Potent Selective Inhibitor of CHK1 Kinase Possessing Unusual N-trifluoromethylpyrazole Pharmacophore Resistant to Metabolic N-dealkylation

  SAMADDER Pounami SUCHÁNKOVÁ Tereza HYLSE Ondřej KHIRSARIYA PrashantKumar NIKULENKOV Fedor DRÁPELA Stanislav STRAKOVÁ Nicol VAŇHARA Petr VAŠÍČKOVÁ Kateřina KOLÁŘOVÁ Hana BINÓ Lucia BITTOVÁ Miroslava OVESNÁ Petra KOLLÁR Peter FEDR Radek EŠNER Milan JAROŠ Josef HAMPL Aleš KREJČÍ Lumír PARUCH Kamil SOUČEK Karel

  Article in Periodical

  Molecular Cancer Therapeutics, year: 2017, volume: 16, edition: 9, DOI