doc. Mgr. Lumír Krejčí, Ph.D.

2020

• DSS1 interacts with and stimulates RAD52 to promote the repair of DSBs

  ŠTEFANOVIE Barbora HENGEL Sarah R. MLČOUŠKOVÁ Jarmila PROCHAZKOVA Jana ŠPÍREK Mário NIKULENKOV Fedor NĚMEČEK Daniel KOCH Brandon G. BAIN Fletcher E. YU Liping SPIES Maria KREJČÍ Lumír

  Article in Periodical

  Nucleic Acids Research, year: 2020, volume: 48, edition: 2, DOI

• RAD51-dependent recruitment of TERRA lncRNA to telomeres through R-loops

  FERETZAKI Marianna POSPÍŠILOVÁ Michaela VALADOR FERNANDES Rita LUNARDI Thomas KREJČÍ Lumír LINGNER Joachim

  Article in Periodical

  Nature, year: 2020, volume: 587, edition: 7833, DOI

• SAMHD1 acts at stalled replication forks to prevent interferon induction

  COQUEL Flavie SILVA Maria-Joao TECHER Hervé ZADOROZHNY Karina SHARMA Sushma NIEMINUSZCZY Jadwiga METTLING Clément DARDILLAC Elodie BARTHE Antoine SCHMITZ Anne-Lyne PROMONET Alexy CRIBIER Alexandra SARRAZIN Amélie NIEDZWIEDZ Wojciech LOPEZ Bernard COSTANZO Vincenzo KREJČÍ Lumír CHABES Andrei BENKIRANE Monsef YEA-LIH Lin PASERO Philippe

  Article in Periodical

  Comptes Rendus - Biologies, year: 2020, volume: 343, edition: 1, DOI

• Substituted propanamides as inhibitors of nucleases

  PARUCH Kamil CARBAIN Benoit Jean-Pierre HAVEL Štěpán VŠIANSKÝ Vít NIKULENKOV Fedor KREJČÍ Lumír

  Patent

  Publisher: European Patent Office, state: Germany, patent's number: EP3556756, year: 2020

• The CHK1 inhibitor MU380 significantly increases the sensitivity of human docetaxel-resistant prostate cancer cells to gemcitabine through the induction of mitotic catastrophe

  DRÁPELA Stanislav KHIRSARIYA PrashantKumar VAN WEERDEN Wytske M FEDR Radek SUCHÁNKOVÁ Tereza BÍZOVA Diana ČERVENÝ Jan HAMPL Aleš PUHR Martin WATSON William R CULIG Zoran KREJČÍ Lumír PARUCH Kamil SOUČEK Karel

  Article in Periodical

  Molecular oncology, year: 2020, volume: 14, edition: 10, DOI

• TREX2 Exonuclease Causes Spontaneous Mutations and Stress-Induced Replication Fork Defects in Cells Expressing RAD51(K133A)

  KO Jun Ho SON Mi Young ZHOU Qing MOLNÁROVÁ Lucia SONG Lambert MLCOUSKOVA Jarmila JEKABSONS Atis MONTAGNA Cristina KREJČÍ Lumír HASTY Paul

  Article in Periodical

  Cell Reports, year: 2020, volume: 33, edition: 12, DOI

2019

• CDK12 controls G1/S progression by regulating RNAPII processivity at core DNA replication genes

  CHIRACKAL MANAVALAN Anil Paul PILAŘOVÁ Květa KLUGE Michael BARTHOLOMEEUSEN Koen RÁJECKÝ Michal OPPELT Jan KHIRSARIYA PrashantKumar PARUCH Kamil KREJČÍ Lumír FRIEDEL Caroline C BLAŽEK Dalibor

  Article in Periodical

  EMBO reports, year: 2019, volume: 20, edition: 9, DOI

• Deficiency and haploinsufficiency of histone macroH2A1.1 in mice recapitulate hematopoietic defects of human myelodysplastic syndrome

  BERESHCHENKO Oxana LO RE Oriana NIKULENKOV Fedor FLAMINI Sara KOTAŠKOVÁ Jana MAZZA Tommaso LE PANNERER Marguerite-Mari BUSCHBECK Marcus GIALLONGO Cesarina PALUMBO Giuseppe LI VOLTI Giovanni PAZIENZA Valerio ČERVINEK Libor RICCARDI Carlo KREJČÍ Lumír POSPÍŠILOVÁ Šárka STEWART A. Francis VINCIGUERRA Manlio

  Article in Periodical

  CLINICAL EPIGENETICS, year: 2019, volume: 11, edition: 1, DOI

• Sumoylation regulates the stability and nuclease activity of Saccharomyces cerevisiae Dna2

  RANJHA Lepakshi LEVIKOVA Maryna ALTMANNOVÁ Veronika KREJČÍ Lumír CEJKA Petr

  Article in Periodical

  COMMUNICATIONS BIOLOGY, year: 2019, volume: 2, edition: MAY 8 2019, DOI

2018

• A residue of motif III positions the helicase domains of motor subunit HsdR in restriction-modification enzyme EcoR124I

  SINHA Dhiraj BIALEVICH Vitali SHAMAYEVA Katsiaryna GUZANOVA Alena SISÁKOVÁ Alexandra CSEFALVAY Eva REHA David KREJČÍ Lumír CAREY Jannette WEISEROVA Marie ETTRICH Rüdiger

  Article in Periodical

  JOURNAL OF MOLECULAR MODELING, year: 2018, volume: 24, edition: 7, DOI