prof. RNDr. Zbyněk Prokop, Ph.D.

2023

• Illuminating the mechanism and allosteric behavior of NanoLuc luciferase

  NEMERGUT Michal PLUSKAL Daniel HORÁČKOVÁ Jana ŠUSTROVÁ Tereza TULIS Jan BÁRTA Tomáš BAATALLAH Racha GAGNOT Glwadys NOVÁKOVÁ Veronika MAJEROVÁ Marika SEDLÁČKOVÁ Karolina MARQUES Sérgio Manuel TOUL Martin DAMBORSKÝ Jiří PROKOP Zbyněk BEDNÁŘ David JANIN Yves L. MAREK Martin

  Article in Periodical

  Nature Communications, year: 2023, volume: 14, edition: 1, DOI

• In-depth analysis of biocatalysts by microfluidics: An emerging source of data for machine learning

  VAŠINA Michal KOVÁŘ David DAMBORSKÝ Jiří YUN Ding YANG Tianjin DE MELLO Andrew MAZURENKO Stanislav STAVRAKIS Stavros PROKOP Zbyněk

  Article in Periodical

  Biotechnology Advances, year: 2023, volume: 66, edition: September 2023, DOI

• Poměr plazminogen/plazmin jako ukazatel bezpečnosti trombolytické léčby

  BRHELOVÁ Eliška SLONKOVÁ Veronika TOUL Martin KOVÁŘ David THALEROVÁ Sandra HLOŽKOVÁ Jana SCHEER Peter AKSU Ahmet Davut OPATŘILOVÁ Radka PROKOP Zbyněk DAMBORSKÝ Jiří MIKULÍK Robert

  Conference abstract

  Year: 2023, type: Conference abstract

• Recognition and coacervation of G-quadruplexes by a multifunctional disordered region in RECQ4 helicase

  PAPAGEORGIOU Anna POSPÍŠILOVÁ Michaela CIBULKA Jakub ASHRAF Raghib WAUDBY Christopher KADEŘÁVEK Pavel MAROZ Volha KUBÍČEK Karel PROKOP Zbyněk KREJČÍ Lumír TRIPSIANES Konstantinos

  Article in Periodical

  Nature Communications, year: 2023, volume: 14, edition: 1, DOI

• The SAP domain of Ku facilitates its efficient loading onto DNA ends

  FULNEČEK Jaroslav KLIMENTOVÁ Eva CAIRO CALZADA Albert BUKOVČÁKOVÁ Soňa ALEXIOU Panagiotis PROKOP Zbyněk ŘÍHA Karel

  Article in Periodical

  Nucleic Acids Research, year: 2023, volume: 51, edition: 21, DOI

2022

• Advanced database mining of efficient haloalkane dehalogenases by sequence and structure bioinformatics and microfluidics

  VAŠINA Michal VAŇÁČEK Pavel HON Jiri KOVÁŘ David FALDYNOVÁ Hana KUNKA Antonín BURYŠKA Tomáš BADENHORST Christoffel P. S. MAZURENKO Stanislav BEDNÁŘ David STAVRAKIS Stavros BORNSCHEUER Uwe T. DEMELLO Andrew DAMBORSKÝ Jiří PROKOP Zbyněk

  Article in Periodical

  Chem Catalysis, year: 2022, volume: 2, edition: 10, DOI

• CalFitter 2.0: Leveraging the power of singular value decomposition to analyse protein thermostability

  KUNKA Antonín LACKO David ŠTOURAČ Jan DAMBORSKÝ Jiří PROKOP Zbyněk MAZURENKO Stanislav

  Article in Periodical

  Nucleic acids research, year: 2022, volume: 50, edition: W1, DOI

• Computer-aided engineering of staphylokinase toward enhanced affinity and selectivity for plasmin

  NIKITIN Dmitri MIČAN Jan TOUL Martin BEDNÁŘ David PEŠKOVÁ Michaela KITTOVÁ Patrícia THALEROVÁ Sandra VÍTEČEK Jan DAMBORSKÝ Jiří MIKULÍK Robert FLEISHMAN Sarel J. PROKOP Zbyněk MAREK Martin

  Article in Periodical

  Computational and Structural Biotechnology Journal, year: 2022, volume: 20, edition: May 2022, DOI

• Droplet-Based Microfluidic Temperature-Jump Platform for the Rapid Assessment of Biomolecular Kinetics

  YANG Tianjin VILLOIS Alessia KUNKA Antonín GRIGOLATO Fulvio AROSIO Paolo PROKOP Zbyněk DEMELLO Andrew STAVRAKIS Stavros

  Article in Periodical

  Analytical chemistry, year: 2022, volume: 94, edition: 48, DOI

• Extended Mechanism of the Plasminogen Activator Staphylokinase Revealed by Global Kinetic Analysis: 1000-fold Higher Catalytic Activity than That of Clinically Used Alteplase

  TOUL Martin NIKITIN Dmitri MAREK Martin DAMBORSKÝ Jiří PROKOP Zbyněk

  Article in Periodical

  ACS Catalysis, year: 2022, volume: 12, edition: 7, DOI