prof. RNDr. Zbyněk Prokop, Ph.D.

2021

• Exploring mechanism of enzyme catalysis by on-chip transient kinetics coupled with global data analysis and molecular modeling

  HESS David DOČKALOVÁ Veronika KOKKONEN Piia Pauliina BEDNÁŘ David DAMBORSKÝ Jiří DEMELLO Andrew PROKOP Zbyněk STAVRAKIS Stavros

  Article in Periodical

  Chem, year: 2021, volume: 7, edition: 4, DOI

• Substrate inhibition by the blockage of product release and its control by tunnel engineering

  KOKKONEN Piia Pauliina BEIER Andy MAZURENKO Stanislav DAMBORSKÝ Jiří BEDNÁŘ David PROKOP Zbyněk

  Article in Periodical

  RSC Chemical Biology, year: 2021, volume: 2, edition: 2, DOI

2020

• A Haloalkane Dehalogenase from Saccharomonospora viridis Strain DSM 43017, a Compost Bacterium with Unusual Catalytic Residues, Unique (S)-Enantiopreference, and High Thermostability

  CHMELOVÁ Klaudia ŠEBESTOVÁ Eva LIŠKOVÁ Veronika BEIER Andy BEDNÁŘ David PROKOP Zbyněk CHALOUPKOVÁ Radka DAMBORSKÝ Jiří

  Article in Periodical

  Applied and Environmental Microbiology, year: 2020, volume: 86, edition: 17, DOI

• An Ultrasensitive Fluorescence Assay for the Detection of Halides and Enzymatic Dehalogenation

  ASLAN-UZEL Askin S. BEIER Andy KOVÁŘ David CZIEGLER Clemens PADHI Santosh K. SCHUITEN Eva D. DORR Mark BOTTCHER Dominique HOLLMANN Frank RUDROFF Florian MIHOVILOVIC Marko D. BURYŠKA Tomáš DAMBORSKÝ Jiří PROKOP Zbyněk BADENHORST Christoffel P. S. BORNSCHEUER Uwe T.

  Article in Periodical

  ChemCatChem, year: 2020, volume: 12, edition: 7, DOI

• EnzymeMiner: automated mining of soluble enzymes with diverse structures, catalytic properties and stabilities

  HON Jiří BORKO Simeon ŠTOURAČ Jan PROKOP Zbyněk ZENDULKA Jaroslav BEDNÁŘ David MARTINEK Tomas DAMBORSKÝ Jiří

  Article in Periodical

  Nucleic acids research, year: 2020, volume: 48, edition: W1, DOI

• Exploration of enzyme diversity: High-throughput techniques for protein production and microscale biochemical characterization

  VAŠINA Michal VAŇÁČEK Pavel DAMBORSKÝ Jiří PROKOP Zbyněk

  Chapter of a book

  Methods in Enzymology - Enzyme Engineering and Evolution: General Methods, year: 2020, number of pages: 35 s.

• Fluorescent substrates for haloalkane dehalogenases: Novel probes for mechanistic studies and protein labeling

  DOČKALOVÁ Veronika MARQUEZ SANCHEZ - CARNERERO Esther Maria DUNAJOVÁ Zuzana PALAO UTIEL Eduardo SLÁNSKÁ Michaela BURYŠKA Tomáš DAMBORSKÝ Jiří KLÁN Petr PROKOP Zbyněk

  Article in Periodical

  Computational and Structural Biotechnology Journal, year: 2020, volume: 18, edition: 2020, DOI

• Machine Learning in Enzyme Engineering

  MAZURENKO Stanislav PROKOP Zbyněk DAMBORSKÝ Jiří

  Article in Periodical

  ACS Catalysis, year: 2020, volume: 10, edition: 2, DOI

• The impact of tunnel mutations on enzymatic catalysis depends on the tunnel-substrate complementarity and the rate-limiting step

  KOKKONEN Piia Pauliina SLÁNSKÁ Michaela DOČKALOVÁ Veronika RANGEL PAMPLONA PIZARRO PINTO José Gaspar MARQUEZ SANCHEZ - CARNERERO Esther Maria DAMBORSKÝ Jiří KLÁN Petr PROKOP Zbyněk BEDNÁŘ David

  Article in Periodical

  Computational and Structural Biotechnology Journal, year: 2020, volume: 18, edition: 2020, DOI

2019

• Controlled Oil/Water Partitioning of Hydrophobic Substrates Extending the Bioanalytical Applications of Droplet-Based Microfluidics

  BURYŠKA Tomáš VAŠINA Michal GIELEN Fabrice VAŇÁČEK Pavel VAN VLIET Liisa JEZEK Jan PILAT Zdenek ZEMÁNEK Pavel DAMBORSKÝ Jiří HOLLFELDER Florian PROKOP Zbyněk

  Article in Periodical

  Analytical Chemistry, year: 2019, volume: 91, edition: 15, DOI