prof. RNDr. Zbyněk Prokop, Ph.D.

2024

• A closed 3D printed microfluidic device for automated growth and differentiation of cerebral organoids from single-cell suspension

  KANDRA Mário VÁŇOVÁ Tereza JONGEN Vincent Alexander POSPÍŠIL Jakub NOVAK Josef CHOCHOLA Václav BURYSKA Tomas PROKOP Zbyněk HODNY Zdenek HAMPL Aleš BOHAČIAKOVÁ Dáša JAROŠ Josef

  Article in Periodical

  Biotechnology Journal, year: 2024, volume: 19, edition: 8, DOI

• Azobenzene-Based Photoswitchable Substrates for Advanced Mechanistic Studies of Model Haloalkane Dehalogenase Enzyme Family

  SLÁNSKÁ Michaela ŠTACKOVÁ Lenka MARQUES Sérgio Manuel ŠTACKO Peter MARTÍNEK Marek JÍLEK Luboš TOUL Martin DAMBORSKÝ Jiří BEDNÁŘ David KLÁN Petr PROKOP Zbyněk

  Article in Periodical

  ACS Catalysis, year: 2024, volume: 14, edition: 15, DOI

• Bacterial Lactonases ZenA with Noncanonical Structural Features Hydrolyze the Mycotoxin Zearalenone

  FRUHAUF Sebastian PUHRINGER Dominic THAMHESL Michaela FAJTL Patricia KUNZ-VEKIRU Elisavet HOBARTNER-GUSSL Andreas SCHATZMAYR Gerd ADAM Gerhard DAMBORSKÝ Jiří DJINOVIC-CARUGO Kristina PROKOP Zbyněk MOLL Wulf-Dieter

  Article in Periodical

  ACS Catalysis, year: 2024, volume: 14, edition: 5, DOI

• CoVAMPnet: Comparative Markov State Analysis for Studying Effects of Drug Candidates on Disordered Biomolecules

  MARQUES Sérgio Manuel KOUBA Petr LEGRAND Anthony Thomas P SEDLAR Jiri DISSON Lucas PLANAS IGLESIAS Joan SANUSI Zainab Kemi KUNKA Antonín DAMBORSKÝ Jiří PAJDLA Tomas PROKOP Zbyněk MAZURENKO Stanislav SIVIC Josef BEDNÁŘ David

  Article in Periodical

  JACS AU, year: 2024, volume: 4, edition: 6, DOI

• Mechanism of BCDX2-mediated RAD51 nucleation on short ssDNA stretches and fork DNA

  AKITA Masaki GIRVAN Paul ŠPÍREK Mário NOVÁČEK Jiří RUEDA David PROKOP Zbyněk KREJČÍ Lumír

  Article in Periodical

  Nucleic acids research, year: 2024, DOI

2023

• Advancing Enzyme's Stability and Catalytic Efficiency through Synergy of Force-Field Calculations, Evolutionary Analysis, and Machine Learning

  KUNKA Antonín MARQUES Sérgio Manuel HAVLÁSEK Martin VAŠINA Michal VELÁTOVÁ Nikola CENGELOVÁ Lucia KOVÁŘ David DAMBORSKÝ Jiří MAREK Martin BEDNÁŘ David PROKOP Zbyněk

  Article in Periodical

  ACS Catalysis, year: 2023, volume: 13, edition: 19, DOI

• Catalytic mechanism for Renilla-type luciferases

  SMITH Andrea TOUL Martin PLUSKAL Daniel BAATALLAH Racha GAGNOT Glwadys RANGEL PAMPLONA PIZARRO PINTO José Gaspar SANTANA Vinicius T. T. STUCHLÁ Markéta NEUGEBAUER Petr CHAIYEN Pimchai DAMBORSKÝ Jiří BEDNÁŘ David JANIN Yves L. L. PROKOP Zbyněk MAREK Martin

  Article in Periodical

  Nature Catalysis, year: 2023, volume: 6, edition: 1, DOI

• Computer-assisted stabilization of fibroblast growth factor FGF-18

  VILÍM Jan GHAZALOVÁ Tereza PETULOVÁ Eliška HORACKOVA Aneta STEPANKOVA Veronika CHALOUPKOVÁ Radka BEDNÁŘ David DAMBORSKÝ Jiří PROKOP Zbyněk

  Article in Periodical

  Computational and Structural Biotechnology Journal, year: 2023, volume: 21, edition: October 2023, DOI

• Domino-like effect of C112R mutation on ApoE4 aggregation and its reduction by Alzheimer’s Disease drug candidate

  NEMERGUT Michal MARQUES Sérgio Manuel UHRÍK Lukáš VÁŇOVÁ Tereza NEZVEDOVÁ Markéta GADARA Darshak Chandulal JHA Durga TULIS Jan NOVÁKOVÁ Veronika PLANAS IGLESIAS Joan KUNKA Antonín LEGRAND Anthony Thomas P HŘÍBKOVÁ Hana POSPÍŠILOVÁ Veronika SEDMÍK Jiří RAŠKA Jan PROKOP Zbyněk DAMBORSKÝ Jiří BOHAČIAKOVÁ Dáša SPÁČIL Zdeněk HERNYCHOVÁ Lenka BEDNÁŘ David MAREK Martin

  Article in Periodical

  Molecular Neurodegeneration, year: 2023, volume: 18, edition: 1, DOI

• Identification, characterization, and engineering of glycosylation in thrombolytics

  TOUL Martin SLONKOVÁ Veronika MIČAN Jan URMINSKÝ Adam Paulin TOMKOVA Maria SEDLÁK Erik BEDNÁŘ David DAMBORSKÝ Jiří HERNYCHOVÁ Lenka PROKOP Zbyněk

  Article in Periodical

  Biotechnology Advances, year: 2023, volume: 66, edition: September 2023, DOI