Mgr. Lenka Dostálová
Research specialist - PhD student, Michal Šmída Research Group
office: bldg. E35/142
Kamenice 753/5
625 00 Brno
phone: | +420 549 49 5875 |
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e‑mail: | Lenka.Dostalova@ceitec.muni.cz |
Total number of publications: 19
2023
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Nově identifikovaná varianta v genu CYCS u rodiny s trombocytopenií typu 4 a její funkční dopad.
Year: 2023, type: Conference abstract
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Varianta v genu CYCS způsobující trombocytopenii 4 zvyšuje kaspázovou aktivitu.
Year: 2023, type: Conference abstract
2022
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Combined drug and CRISPR/CAS9 screening reveals specific targets for SF3B1- and NOTCH1- mutated CLL cells.
Year: 2022, type: Conference abstract
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CRISPR/Cas9 knockout screening revealed genes involved in CD20 regulation.
Year: 2022, type: Conference abstract
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Chasing the epigenetic landscape to enhance CAR-T cell activity by preventing CD19 antigen escape in relapsed models.
Year: 2022, type: Conference abstract
2021
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CD19 promoter hypermethylation as means of antigen-negative escape to CART-19 therapy.
Year: 2021, type: Conference abstract
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Hypermethylation of CD19 promoter enables antigen-negative escape to CART-19 in vivo and in vitro
Journal for ImmunoTherapy of Cancer, year: 2021, volume: 9, edition: 8, DOI
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In vivo antigen-negative escape to CART-19 caused by CD19 promotor hypermethylation.
Year: 2021, type: Conference abstract
2020
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Genome-wide CRISPR/Cas9 screening reveals novel target genes, whose inactivation is able to upregulate surface expression of immunotherapy target CD20
Year: 2020, type: Conference abstract