Project information
New trends in electrochemistry of nucleic acids and their applications in enviromental chemistry
- Project Identification
- GA203/02/0422
- Project Period
- 1/2002 - 12/2004
- Investor / Pogramme / Project type
-
Czech Science Foundation
- Standard Projects
- MU Faculty or unit
- Faculty of Science
- Cooperating Organization
-
Institute of Biophysics
- Responsible person RNDr. František Jelen, CSc.
Electrochemical methods represent fast and inexpensive approach in studies of structure, interactions and properties of biomacromolecules. In this project modem electrochemical techniques will be applied in connection with mercury and solid electrodes to study oligonucleotides and nucleic acids and then-interactions with some drugs and carcinogens. Information on the adsorption and redox properties of oligonucleotides with respect to their nucleotide sequences and lengths will be obtained. Electrochemica studies will concentrate also on interaction of the nucleic acids strands at the electrode surface aimed for developing sensors for various kind of nucleic acid damage and detection of genotoxic compounds in environment.
Publications
Total number of publications: 59
2005
-
Determination of picogram quantities of oligodeoxynucleotides by stripping voltammetry at mercury modified graphite electrode surfaces
J.Electroanal.Chem., year: 2005, volume: 577, edition: 3
-
Porovnanie mechanizmu vylučovania niklu z chloridového a síranového elektrolytu na grafitovej elektróde
Sborník V. Pracovního setkání fyzikálních chemiku a elektrochemiku, year: 2005
-
Study of the influence of boric acid on the Cd2+ reduction process by elimination voltammetry with linear scan
Sborník V. Pracovního setkání fyzikálních chemiku a elektrochemiku, year: 2005
-
The protonation/deprotonation equilibrium of azido-analogues of thymidine and uridine studied by UV spectroscopy and chemometrics
sborník přispěvků- V. Pracovní setkání fyzikálních chemiků a elektrochemiků, year: 2005
2004
-
Analysis of phytochelatin (g-Glu-Cys)2-Gly by a multi-channel electrochemical detector in online connection with reversed-phase liquid chromatography
Book of Abstracts I - 55th Annual Meeting of the ISE, year: 2004
-
Analýza thiolových sloučenin pomocí vysoko-učinné kapalinové chromatografie s elektrochemickou detekcí
Sborník abstrakt IV pracovní setkání fyzikálních chemiků a elektrochemiků, year: 2004
-
Application of elimination voltammetry in the study of electroplating processes on the graphite electrode
Electrochimica Acta, year: 2004, volume: 49, edition: 1
-
Application of elimination voltammetry with linear scan to the study of electrochemical reactions of metal ions on various electrodes
Book of Abstrakt, 55th Annual Meeting of the International Society of Electrochemistry, year: 2004
-
Application of elimination voltammetry with linear scan to the study of reduction of cadmium on various electrodes
Sborník příspěvků IV. pracovní setkání fyzikálních chemiků a elektrochemiků, year: 2004
-
Current elimination coefficient beta
Sborník příspěvků IV. pracovního setkání fyzikálních chemiků a elektrochemiků, year: 2004