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Project information
New trends in electrochemistry of nucleic acids and their applications in enviromental chemistry

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Project Identification
GA203/02/0422
Project Period
1/2002 - 12/2004
Investor / Pogramme / Project type
Czech Science Foundation
  • Standard Projects
MU Faculty or unit
Faculty of Science
Cooperating Organization
Institute of Biophysics
  • Responsible person RNDr. František Jelen, CSc.

Electrochemical methods represent fast and inexpensive approach in studies of structure, interactions and properties of biomacromolecules. In this project modem electrochemical techniques will be applied in connection with mercury and solid electrodes to study oligonucleotides and nucleic acids and then-interactions with some drugs and carcinogens. Information on the adsorption and redox properties of oligonucleotides with respect to their nucleotide sequences and lengths will be obtained. Electrochemica studies will concentrate also on interaction of the nucleic acids strands at the electrode surface aimed for developing sensors for various kind of nucleic acid damage and detection of genotoxic compounds in environment.

Publications

Total number of publications: 59

2004

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