Project information
Molecular diagnostic, epidemiology and classification of pathogenic Gram positive cocci
- Project Identification
- GA301/02/1505
- Project Period
- 1/2002 - 12/2004
- Investor / Pogramme / Project type
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Czech Science Foundation
- Standard Projects
- MU Faculty or unit
- Faculty of Science
- Cooperating Organization
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University Hospital Brno-Bohunice
- Responsible person MUDr. Alena Ševčíková
- Responsible person RNDr. Petr Petráš, CSc.
Gram positive cocci represent a phylogenetically very heterogeneous bacterial group with a high phenotypic variability inside species complicating their identification. The strains of Gram positive cocci isolated from human clinical materials as pathogens will be studied in this project. The lactic acid bacteria from sepsis (mainly Leuconostoc and Pediococcus genera which are naturally resistant to vancomycin), methicillin resistant Staphylococcus aureus isolated from nosocomial infections and multiresistant strains of Staphylococcus sciuri complex from human infections (natural reservoir of mecA gene) will be analysed. The main aim of the project is application of modern molecular methods based on genome analysis and their using for quick and reliable identification of mentioned pathogens and development of new methods for their molecular typing. Moreover, all isolates will be characterised by biotyping, antibiograms and whole-cell protein profiles analysis. The detailed taxonomic classifica
Publications
Total number of publications: 32
2007
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Identification of lactic acid bacteria isolated from human blood cultures
FEMS immunology and medical microbiology, year: 2007, volume: 49, edition: 2
2006
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Molekulární diagnostika a epidemiologie MRSA II
Year: 2006, type: Appeared in Conference without Proceedings
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Staphylococcus equorum and Staphylococcus succinus isolated from human clinical specimens
Journal of Medical Microbiology, year: 2006, volume: 55, edition: 5
2005
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Characterization of presumptive Staphylococcus xylosus strains by SDS-PAGE protein profiles.
IX. Pracovní setkání biochemiků a molekulárních biologů. Sborník příspěvků., year: 2005
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Identification of lactic acid bacteria isolated from blood samples and their susceptibility to antibiotics
Year: 2005, type: Conference abstract
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Identification of Staphylococcus piscifermentans from dog feces
Folia Microbiologica, year: 2005, volume: 50, edition: 6
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Molekulárně-biologická charakteristika lyzogenizujích bakteriofágů
Informační listy Genetické společnosti Gregora Mendela, year: 2005, volume: 28, edition: 1
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<I>Staphylococcus simiae </I>sp. nov., isolated from South American squirrel monkeys
International Journal of Systematic and Evolutionary Microbiology, year: 2005, volume: 55, edition: 5
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Weissella confusa (basonym Lactobacillus confusus) - první záchyt z hemokultury v České republice
Zprávy CEM (SZÚ, Praha), year: 2005, volume: 14, edition: 1
2004
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Comparative phage genomics of family <I>Siphoviridae</I> in <I>Staphylococcus aureus</I>
11th International Symposium on Staphylococci & Staphylococcal Infections. Plenary Summaries & Poster Abstracts, year: 2004