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Project information
Molecular diagnostic, epidemiology and classification of pathogenic Gram positive cocci

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Project Identification
GA301/02/1505
Project Period
1/2002 - 12/2004
Investor / Pogramme / Project type
Czech Science Foundation
  • Standard Projects
MU Faculty or unit
Faculty of Science
Cooperating Organization
University Hospital Brno-Bohunice
  • Responsible person MUDr. Alena Ševčíková
National Institute of Public Health Prague 10 - Vinohrady
  • Responsible person RNDr. Petr Petráš, CSc.

Gram positive cocci represent a phylogenetically very heterogeneous bacterial group with a high phenotypic variability inside species complicating their identification. The strains of Gram positive cocci isolated from human clinical materials as pathogens will be studied in this project. The lactic acid bacteria from sepsis (mainly Leuconostoc and Pediococcus genera which are naturally resistant to vancomycin), methicillin resistant Staphylococcus aureus isolated from nosocomial infections and multiresistant strains of Staphylococcus sciuri complex from human infections (natural reservoir of mecA gene) will be analysed. The main aim of the project is application of modern molecular methods based on genome analysis and their using for quick and reliable identification of mentioned pathogens and development of new methods for their molecular typing. Moreover, all isolates will be characterised by biotyping, antibiograms and whole-cell protein profiles analysis. The detailed taxonomic classifica

Publications

Total number of publications: 32

2004

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