Project information
Dynamika vzniku shelterinového komplexu
- Project Identification
- GAP205/12/0550
- Project Period
- 1/2012 - 12/2015
- Investor / Pogramme / Project type
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Czech Science Foundation
- Standard Projects
- MU Faculty or unit
- Central European Institute of Technology
Charakterizace afinity komponent proteinu a DNA v ramci shelterinoveho komplexu; navrzeni kinetickeho modelu sestavovani shelterinu na telomerove DNA; stanoven limitujicich molekularnich interakci pro komplexaci shelterinu; urceni vlivu chemoterapeutik na vazbu shelterinovych podjednotek na DNA.
Publications
Total number of publications: 17
2014
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TRF1 negotiates TTAGGG repeat-associated replication problems by recruiting the BLM helicase and the TPP1/POT1 repressor of ATR signaling
GENES & DEVELOPMENT, year: 2014, volume: 28, edition: 22, DOI
2013
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53BP1 Regulates DSB Repair Using Rif1 to Control 5 ' End Resection
Science, year: 2013, volume: 339, edition: 6120, DOI
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How does protein Rap1 affect interactions of its binding partner TRF2?
Year: 2013, type: Conference abstract
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Impact of N-terminal basic domain of protein TRF2 on its DNA binding affinity
Year: 2013, type: Conference abstract
2012
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Serine phosphorylation and proline isomerization in RNAP II CTD control recruitment of Nrd1
Genes & Development, year: 2012, volume: 26, edition: 17, DOI
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Stanovení vlivu bazické domény lidského telomerového proteinu TRF2 na vazbu k DNA
XII mezioborové setkání mladých biologů, biochemiků a chemiků z Čech a Slovenska, year: 2012
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Synergism of the Two Myb Domains of Tay1 Protein Results in High Affinity Binding to Telomeres*
The Journal of Biological Chemistry, year: 2012, volume: 287, edition: 38, DOI