Project information
Determination of markers, screening and early diagnostics of cancer diseases using highly automated processing of multidimensional biomedical images
(Biomarker)
- Project Identification
- 2B06052
- Project Period
- 7/2006 - 6/2011
- Investor / Pogramme / Project type
-
Ministry of Education, Youth and Sports of the CR
- Health and quality of life
- MU Faculty or unit
- Faculty of Informatics
- Keywords
- zpracování obrazu; optická mikroskopie; buněčné jádro; prostorové uspořádání; exprese genů; mikročipy; nádorová onemocnění; diagnostické markery
- Cooperating Organization
-
Brno University of Technology
- Responsible person doc. RNDr. Pavel Smrž, Ph.D.
- Responsible person Ing. Miloslav Richter, Ph.D.
The aim of the project is to develop new approaches to the processing of image data from fluorescence microscopy and microarrays that, in combination with the research in genomics and proteomics techniques, will help with the determination of markers, screening and early diagnostics of cancer diseases.
Results
Publications
Total number of publications: 121
2009
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Combination of mRNA and protein microarray analysis in complex cell profiling
Neoplasma, year: 2009, volume: 2/2009, edition: 56
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CytoPacq
Year: 2009
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CytoPacq – On-line Framework for Simulating Fluorescence Microscopy Images
Year: 2009, type:
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Free tools for automated cell image acquisition and analysis
Year: 2009, type:
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Generation of Digital Phantoms of Cell Nuclei and Simulation of Image Formation in 3D Image Cytometry
Cytometry Part A, year: 2009, volume: 75A, edition: 6, DOI
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Information Content Analysis in Automated Microscopy Imaging using an Adaptive Autofocus Algorithm for Multimodal Functions
Journal of Microscopy, year: 2009, volume: 236, edition: 3, DOI
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Insulin Decreases Transcription of Three Proteins Associated with Lung Surfactant
Year: 2009, type: R&D Presentation
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MEK inhibition enhances BMS-214662-induced apoptosis in primitive CD34+ CML stem/progenitor cells.
Year: 2009, type: Conference abstract
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Microarray analysis using limited amount of cells
Folia Biologica (Praha), year: 2009, volume: 2009, edition: 55
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Prediction of localization and interactions of apoptotic proteins
Journal of Biomedical Science, year: 2009, volume: 16, edition: 59