Project information
Environment - carcinogenesis - oncology
- Project Identification
- MSM 141100003
- Project Period
- 1/1999 - 1/2004
- Investor / Pogramme / Project type
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Ministry of Education, Youth and Sports of the CR
- Research Intents
- MU Faculty or unit
- Faculty of Medicine
- Keywords
- environmental pollutants; genotoxic agents; mechanisms of genomic and extragenomic carcinogenesis; predictive bioparameters ; optimization of oncological therapy
The aim of this multidisciplinary project is to contribute to the research of the mechanisms of carcinogenesis with a special interest devoted to reduction of risks from environmental pollutants and genotoxic effects of therapeutic agents. The investigation of effects of persistent organic pollutants and other genotoxic compounds on induction and development of malignant tumors. The special interest will be paid also to the process of extragenomic carcinogenesis. Biomathematical analysis of risks of genotoxicity in their real proportions, which couples the data from basic environmental reasearch, toxicology, experimental biology and clinical oncology. Multivariate mathematical analysis of oncological bioparameters directed mainly to prediction of the efficacy of treatment in different types of tumors and optimization of therapeutic regimens.
Publications
Total number of publications: 670
2001
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Emisní inventura POPs (PAHs, PCBs, PCDDs/Fs, HCB) v České republice
Ochrana ovzduší, year: 2001, volume: 13, edition: 1
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Emisní inventura POPs (PAHs, PCBs, PCDDs/Fs, HCB) v České Republice
OVZDUŠÍ 2001 - Program a sborník konference, year: 2001
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Environmental Programme at the Faculty of Chemistry, Brno University of Technology.
2. Mezinárodní konference Ekonomika, logistika, ekologie v ozbrojených silách, Brno 2001, Sborník, year: 2001
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Flowcytometrický DNA profil nádorů - aplikace v klinické onkologii
Sborník konference Analytická cytometrie I, year: 2001
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GEF Regional based assessment on persistent toxic substances
OVZDUŠÍ 2001 - Program a sborník konference, year: 2001
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High dose rate intraluminal brachyterapy in the treatment of malignant airway obstructions
Neoplasma, year: 2001, volume: 48, edition: 2
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Hodnocení výsledků onkologické péče z reálných klinických dat - limity a úskalí
Sborník konference XXV. Brněnské Onkologické Dny, year: 2001
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HPLC separace chlorfenolů na koloně malého průměru pro stanovení v povrchových vodách
Sborník 53. Zjazdu chemických spoločností, year: 2001
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Challenges of educating engineers for sustainable development entering the 21st century
INES & Heinrich Böll Foundation Symposium: Ten Years after Rio, Sborník, year: 2001
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Characterization of dioxin-like activity of riverine sediments from the Czech Republic
Environmental Toxicology and Chemistry, year: 2001, volume: 20, edition: 8