Project information
Interaction of humic substances and UV-VIS irradiation with dioxin-like environmental pollutants
- Project Identification
- GP525/08/P464
- Project Period
- 1/2008 - 12/2010
- Investor / Pogramme / Project type
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Czech Science Foundation
- Postdoctoral projects
- MU Faculty or unit
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Faculty of Science
- RNDr. Mgr. Michal Bittner, Ph.D.
- Mgr. Veronika Jálová, Ph.D.
- Mgr. Tereza Štěpánková, Ph.D.
- Keywords
- humic substances, AhR-mediated toxicity, dioxin-like toxicity, irradiation, environmental pollutants
Humic substances (HS) are naturally occurring compounds ubiquitous in water, that were shown e.g. to interact with xenobiotics. In consequence of this interaction, properties of afected compounds such as bioavailability and toxicity are changed. Another important environmental factor affecting properties of both HS and xenobiotics is solar irradiation. Among highly hazardous xenobiotics belong dioxin-like compounds such as polychlorinated dioxins, furans and biphenyls, and polycyclic aromatic hydrocarbons. Despite the numerous studies both on HS and dioxin-like substances, and potential irradiation impact, there has not been published any information on alteration of dioxin-like toxicity both by HS and irradiation yet. The project will bring priority ecotoxicological information on changed of dioxin-like toxicity under the influence of HS and irradiation. New method of HS isolation from aquatic environment and new fish model cell line RLT2.0 will be introduced to increase the environmental relevance of obtained results. The final output will be also good quality publications, enhancement of scientific work experience of the applicant, and the methodical development of the research centre.
Publications
Total number of publications: 8
2011
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Enhancement of AhR-mediated activity of selected pollutants and their mixtures after interaction with dissolved organic matter
Environment International, year: 2011, volume: 37, edition: 5, DOI
2010
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Enhancement of toxicity of selected POPs and its mixtures in consequence of interaction with dissolved organic matter
Year: 2010, type: Conference abstract
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Zvýšení toxicity perzistentních organických polutantů v přítomnosti huminových látek
Bulletin VÚRH Vodňany, year: 2010, volume: 46, edition: 1
2009
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Enhancement of toxicity of various POPs in consequence of interaction with dissolved humic substances
Year: 2009, type: Conference abstract
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In vitro assessment of AhR-mediated activities of TCDD in mixture with humic substances
Chemosphere, year: 2009, volume: 76, edition: 11
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Metody izolace rozpuštěné oganické hmoty z vod
Bulletin VÚRH, year: 2009, volume: 4, edition: 4
2008
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IN VITRO ASSESSMENT OF INTERACTION OF HUMIC SUBSTANCES WITH 2,3,7,8-TCDD
Year: 2008, type: Conference abstract
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Physiological effects of humic substances - danger or benefit?
Environmental changes and biological assessment IV. Scripta Facultatis Rerum Naturalium Universitatis Ostraviensis Nr. 391, year: 2008