Project information
Biochemie na rozcestí mezi in silico a in vitro
- Project Identification
- GD203/09/H046
- Project Period
- 1/2009 - 12/2012
- Investor / Pogramme / Project type
-
Czech Science Foundation
- Doctor grants
- MU Faculty or unit
- Faculty of Science
- Cooperating Organization
-
Palacký University, Olomouc
- Responsible person prof. RNDr. Michal Otyepka, Ph.D.
Publications
Total number of publications: 29
2012
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Understanding the Sequence Preference of Recurrent RNA Building Blocks using Quantum Chemistry: The Intrastrand RNA Dinucleotide Platform
Journal of Chemical Theory and Computation, year: 2012, volume: 8, edition: 1, DOI
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Unwinding of synthetic replication and recombination substrates by Srs2
DNA Repair, year: 2012, volume: 11, edition: 10, DOI
2011
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Noncanonical Hydrogen Bonding in Nucleic Acids. Benchmark Evaluation of Key Base-Phosphate Interactions in Folded RNA Molecules Using Quantum-Chemical Calculations and Molecular Dynamics Simulations
JOURNAL OF PHYSICAL CHEMISTRY A, year: 2011, volume: 115, edition: 41, DOI
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QM/MM Studies of Hairpin Ribozyme Self-Cleavage Suggest the Feasibility of Multiple Competing Reaction Mechanisms
JOURNAL OF PHYSICAL CHEMISTRY B, year: 2011, volume: 115, edition: 47, DOI
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Reconstitution of DNA repair synthesis in vitro and the role of polymerase and helicase activities
DNA Repair, year: 2011, volume: 10, edition: 6, DOI
2010
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Cdk1 targets Srs2 to complete synthesis-dependent strand annealing and to promote
PLoS Genetics, year: 2010, volume: 2010, edition: 2
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Rad52 SUMOylation affects the efficiency of the DNA repair
Nucleic Acids Research, year: 2010, volume: 38, edition: 6
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Srs2: the Odd-Job Man in DNA repair
DNA Repair, year: 2010, volume: 9, edition: 3
2009
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Co-operativity of Mus81-Mms4 with Rad54 in the resolution of recombination and replication intermediates.
J Biol Chem., year: 2009, volume: 284, edition: 12
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DNA OPRAVA A NESTABILITA GENOMU
Year: 2009, type: R&D Presentation