Publication details

Studie TECOS

Title in English The TECOS study
Authors

ŠPINAR Jindřich ŠPINAROVÁ Lenka VÍTOVEC Jiří

Year of publication 2015
Type Article in Periodical
Magazine / Source Hypertenze & kardiovaskulární prevence
MU Faculty or unit

Faculty of Medicine

Citation
Field Cardiovascular diseases incl. cardiosurgery
Keywords diabetes melolitut; sitagliptin; heart failure
Description The TECOS study demonstrated in 14 671 that sitagliptin - dipeptilpetidas inhibitor 4 - is an effective and safe drug in patients with diabeters mellitus. The glycosylated haemoglobin decreased by 0,29% and the primary cardiovascular endpoint appeared in 839 (11,4%) patients on sitagliptin and in 851 (11,6%) patients on placebo (p < 0,001). There was no increase in heart failure hospitalisation.

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