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Publication details
The C766T low-density lipoprotein receptor related protein polymorphism and coronary artery disease, plasma lipoproteins, and longevity in the Czech population
Authors | |
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Year of publication | 2001 |
Type | Article in Periodical |
Magazine / Source | Journal of Molecular Medicine |
MU Faculty or unit | |
Citation | |
Field | Genetics and molecular biology |
Keywords | Low density lipoprotein receptor related protein; Plasminogen activator inhibitor 1; Coronary artery disease; Genetic polymorphism; Longevity; Plasma lipoproteins |
Description | Our results demonstrate that the T allele of the C766T LRP polymorphism is negatively related to longevity, and that it increases the risk of CAD development in subjects with the 5G/5G PAI-1 genotype. No significant association was observed between the LRP or PAI-1 polymorphisms and plasma lipoprotein levels in the CAD patients. |
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