Publication details
Akutní lymfoblastická leukémie u kojenců
| Title in English | Acute Lymphoblastic Leukemia in Infants |
|---|---|
| Authors | |
| Year of publication | 2002 |
| Type | Article in Periodical |
| Magazine / Source | Transfúz. Hemat. dnes |
| MU Faculty or unit | |
| Citation | |
| Field | Paediatry |
| Keywords | acute lymphoblastic leukemia; infants; t(4:11); fusion gene MLL-AF4 |
| Description | The therapeutic results in children with acute lymphoblastic leukaemia (ALL) are improving continuously with modern treatment protocols of combined chemotherapy. Approximately 75% children and adolescents can be cured from their leukaemia. Among infants younger than one year ALL is a rare disease. Typical infant ALL originates from very early precursors of B cells with a specific genotype, large leukaemic mass on diagnosis and high risk of early relapse. Between 1990-2000, 671 children and adelescents 0-18 years old |