Association of the Cluster of Genetic Risk Factors in Loci Related to Glycoxidation with Diabetic Nephropathy in Type 2 Diabetes Mellitus

• Authors: KAŇKOVÁ Kateřina; STEJSKALOVÁ Andrea; PÁCAL Lukáš; HERTLOVÁ Miluše; KRUSOVÁ Darja
• Year of publication: 2005
• Type: Conference abstract
• MU Faculty or unit: Faculty of Medicine
• Description: We found significant association of selected genetic variants in the RAGE, SOD2 and PARP-1 genes with the presence of DN in type 2 diabetics and, in the case of RAGE and PARP-1, also with acceleration of DN onset. We therefore conclude that those htSNPs could be regarded disease markers of DN.

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