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Informace o publikaci
1H, 13C, and 15N chemical shift assignments of ZCCHC9
Autoři | |
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Rok publikování | 2010 |
Druh | Článek v odborném periodiku |
Časopis / Zdroj | Biomolecular NMR Assignments |
Fakulta / Pracoviště MU | |
Citace | |
www | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3049224/ |
Doi | http://dx.doi.org/10.1007/s12104-010-9257-2 |
Obor | Genetika a molekulární biologie |
Klíčová slova | ZCCHC9; Zinc knuckle; CCHC; RNA degradation |
Popis | ZCCHC9 is a human nuclear protein with sequence homology to yeast Air1p/Air2p proteins which are RNA-binding subunits of the Trf4/Air2/Mtr4 polyadenylation (TRAMP) complex involved in nuclear RNA quality control and degradation in yeast. The ZCCHC9 protein contains four retroviral-type zinc knuckle motifs. Here, we report the NMR spectral assignment of the zinc knuckle region of ZCCHC9. These data will allow performing NMR structural and RNA-binding studies of ZCCHC9 with the aim to investigate its role in the RNA quality control in human. |
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