RNDr. Pavel Krejčí, Ph.D.

2012

• Sixteen years and counting: the current understanding of fibroblast growth factorreceptor 3 (FGFR3) signaling in skeletal dysplasias.

  FOLDYNOVA-TRANTIRKOVA Silvie WILCOX W.R. KREJČÍ Pavel

  Article in Periodical

  Human Mutation, year: 2012, volume: 33, edition: 1, DOI

• Způsob stanovení závažnosti a prognózy B-buněčné chronické lymfocytární leukémie

  BRYJA Vítězslav KREJČÍ Pavel KAUCKÁ Markéta POSPÍŠILOVÁ Šárka MAYER Jiří KOZUBÍK Alois MALINOVÁ Karla KOTAŠKOVÁ Jana

  Patent

  Publisher: , state: Czech Republic, patent's number: 303555, year: 2012

2011

• Mitogen-Activated Protein Kinases Promote WNT/beta-Catenin Signaling via Phosphorylation of LRP6

  ČERVENKA Igor WOLF Joshua MAŠEK Jan KREJČÍ Pavel WILCOX William R KOZUBÍK Alois SCHULTE Gunnar GUTKIND J Silvio BRYJA Vítězslav

  Article in Periodical

  January 2011, year: 2011, volume: 31, edition: 1, DOI

• Post-translational modifications regulate signalling by Ror1

  KAUCKÁ Markéta KREJČÍ Pavel PLEVOVÁ Karla PAVLOVÁ Šárka PROCHÁZKOVÁ Jiřina JANOVSKÁ Pavlína VALNOHOVÁ Jana KOZUBÍK Alois POSPÍŠILOVÁ Šárka BRYJA Vítězslav

  Article in Periodical

  Acta Physiologica, year: 2011, volume: 203, edition: 3, DOI

• Sequential activation and inactivation of dishevelled in the Wnt/{beta}-catenin pathway by casein kinases.

  BERNATÍK Ondřej GANJI Sri Ranjani DIJKSTERHUIS Jacomijn KONIK Peter ČERVENKA Igor POLONIO Tilman KREJČÍ Pavel SCHULTE Gunnar BRYJA Vítězslav

  Article in Periodical

  Journal of Biological Chemistry, year: 2011, volume: 286, edition: 12, DOI

• The novel JAK inhibitor AZD1480 blocks STAT3 and FGFR3 signaling, resulting insuppression of human myeloma cell growth and survival.

  SCUTO A. KREJČÍ Pavel POPPLEWELL L. WU J. WANG Y. KUJAWSKI M. KOWOLIK C. XIN H. CHEN L. WANG Y. KRETZNER L. YU H. WILCOX W.R. YEN Y. FORMAN S. JOVE R.

  Article in Periodical

  Leukemia, year: 2011, volume: 25, edition: 3, DOI

• Wnt/PCP pathway regulates B-cell migration in chronic lymphocytic leukemia

  KAUCKÁ Markéta VERNER Jan PROCHÁZKOVÁ Jiřina PLEVOVÁ Karla STEHLÍKOVÁ Olga KREJČÍ Pavel KOZUBÍK Alois MAYER Jiří POSPÍŠILOVÁ Šárka BRYJA Vítězslav

  Conference abstract

  Year: 2011, type: Conference abstract

2010

• Breast cancer-specific mutations in CK1epsilon inhibit Wnt/beta-catenin and activate the Wnt/Rac1/JNK and NFAT pathways to decrease cell adhesion and promote cell migration.

  FOLDYNOVÁ-TRANTÍRKOVÁ S. SEKYROVÁ P. TMEJOVÁ Kateřina BRUMOVSKÁ E. BERNATÍK Ondřej BLANKENFELDT W. KREJČÍ Pavel KOZUBÍK Alois DOLEZAL T. TRANTÍREK Lukáš BRYJA Vítězslav

  Article in Periodical

  Breast Cancer Research, year: 2010, volume: 2010, edition: 12/3, DOI

• FGFR3 signaling induces a reversible senescence phenotype in chondrocytes similar to oncogene-induced premature senescence

  KREJČÍ Pavel PROCHÁZKOVÁ Jiřina SMUTNÝ Jiří CHLEBOVÁ Katarína LIN Patricia AKLIAN Anie BRYJA Vítězslav KOZUBÍK Alois WILCOX William R.

  Article in Periodical

  Bone, year: 2010, volume: neuveden, edition: 47

• Negative regulation of Wnt signaling mediated by CK1- phosphorylated Dishevelled via Ror2

  WITTE Florian BERNATÍK Ondřej KIRCHNER Katharina MAŠEK Jan MAHL Annika KREJČÍ Pavel MUNDLOS Stefan SCHAMBONY Alexandra BRYJA Vítězslav STRICKER Sigmar

  Article in Periodical

  FASEB JOURNAL, year: 2010, volume: 24, edition: 7, DOI